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KMID : 1007519990080050329
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Food Science and Biotechnology
1999 Volume.8 No. 5 p.329 ~ p.332
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Chemical Structure of Angiotensin converting Enzyme Inhibitor Isolated from Onion Flesh
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Suh, Hyung Joo
Chung, Soo Hyun/Kim, Kyung Mi/Cho, Won Dai/Ma, Sang Jo
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Abstract
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From the methanol extract of onion flesh, four major flavonols (F₁, F₂, F₃and F₄) were separated by Sephadex LH20 column chromatography. F₃ fraction was found to have a high inhibitory effect on ACE activity. Based on the ultraviolet-visible absorption spectroscopy, F₃ fraction was conjectured to be a flavonol with 3,5,7,3´-tetrahydroxy group. After acid hydrolysis of the fraction, F3 was found to consist of quercetin and glucose. Through FAB-MS analysis, F₃was finally confirmed as quercetin 4´-glucoside.
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